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New 2-Phenylquinoline Derivatives: Synthesis and Preliminary Evaluation as Antimicrobial Agents

[ Vol. 9 , Issue. 5 ]

Author(s):

Saida Benzerka, Abdelmalek Bouraiou, Sofiane Bouacida, Thierry Roisnel, Chafia Bentchouala, Farida Smati and Ali Belfaitah   Pages 309 - 313 ( 5 )

Abstract:


A number of new 2-phenylquinoline derivatives have been synthesized. All the synthesized compounds were evaluated for their antibacterial activity. Most of them showed a good activity against Escherichia coli and Staphylococcus aureus. The minimum inhibitory concentration (MIC) was determined for tested compounds.

Keywords:

2-Phenylquinoline, antibacterial activity, minimum inhibitory concentration, suzuki coupling, antimalarial, anti - inflammatory, a nticancer, antibiotic, antihypertensive, tyrokinase

Affiliation:

Laboratoire des Produits Naturels d’Origine Vegetale et de Synthese Organique, Universite Mentouri-Constantine, 25000, Algerie.



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