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Microwave and Classical Activation of Solvent-Free Reactions of NIsopropyl Arylidene Amines with Alkyl Cyanoacetates

[ Vol. 2 , Issue. 4 ]

Author(s):

Ludovic Paquin, Loic Toupet, Jack Hamelin and Francoise Texier-Boullet   Pages 334 - 339 ( 6 )

Abstract:


Neat imine 1a with alkylcyanoacetate 2 leads to new cyclohexenes by Michael-Michael initiated ring closure reaction at RT or under classical heating. Surprisingly, this cyclohexene is not formed under microwave. This is the first example of a reaction working under classical activation and not under microwaves. A mechanism and an explanation are proposed.

Keywords:

physical organic chemistry, solvent-free reactions, non thermal microwave effect, cyclohexenes, electrophilic alkenes

Affiliation:

Synthese et Electrosynthese Organiques 3, Associe au CNRS, UMR 6510, Universite de Rennes I,Campus de Beaulieu, 35042 Rennes France.



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