Ludovic Paquin, Loic Toupet, Jack Hamelin and Francoise Texier-Boullet Pages 334 - 339 ( 6 )
Neat imine 1a with alkylcyanoacetate 2 leads to new cyclohexenes by Michael-Michael initiated ring closure reaction at RT or under classical heating. Surprisingly, this cyclohexene is not formed under microwave. This is the first example of a reaction working under classical activation and not under microwaves. A mechanism and an explanation are proposed.
physical organic chemistry, solvent-free reactions, non thermal microwave effect, cyclohexenes, electrophilic alkenes
Synthese et Electrosynthese Organiques 3, Associe au CNRS, UMR 6510, Universite de Rennes I,Campus de Beaulieu, 35042 Rennes France.