Srinivas Chittaboina, Blake Hodges and Qian Wang Pages 35 - 38 ( 4 )
The regioselective 1-O-deacetylation of peracetylated carbohydrates with ammonium acetate in DMF (or a mixed solution of tetrahydrofuran and methanol) is described. It offers a facile and efficient way to prepare O-acetylpyranosides presenting one free hydroxyl group at the anomeric position.
Carbohydrates, regioselectivity, glycosides, acylation, glycosylations
Department of Chemistryand Biochemistry, University of South Carolina, 631 Sumter Street,Columbia, SC 29208, USA.