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A Facile Route for the Regioselective Deacetylation of Peracetylated Carbohydrates at Anomeric Position

[ Vol. 3 , Issue. 1 ]


Srinivas Chittaboina, Blake Hodges and Qian Wang   Pages 35 - 38 ( 4 )


The regioselective 1-O-deacetylation of peracetylated carbohydrates with ammonium acetate in DMF (or a mixed solution of tetrahydrofuran and methanol) is described. It offers a facile and efficient way to prepare O-acetylpyranosides presenting one free hydroxyl group at the anomeric position.


Carbohydrates, regioselectivity, glycosides, acylation, glycosylations


Department of Chemistryand Biochemistry, University of South Carolina, 631 Sumter Street,Columbia, SC 29208, USA.

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