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Ag(I)-promoted Decarboxylative Annulation of α-oxocarboxylic Acids with (E)-3-(2-aminophenyl)-1-phenylprop-2-en-1-ones Toward 3,4- Functionalized Quinolines

[ Vol. 18 , Issue. 10 ]

Author(s):

Xiaodong Fan, Chang Wang and Jiang Cheng*   Pages 777 - 782 ( 6 )

Abstract:


An efficient Ag-promoted decarboxylative cyclization of α-oxocarboxylic acids with (E)-3- (2-aminophenyl)-1-phenylprop-2-en-1-ones has been developed to afford a series of functionalized quinolines in moderate to good yields. This method was compatible with a variety of functional groups and provided an attractive method toward phenyl(2-phenylquinolin-3-yl)methanones.

Keywords:

α-oxocarboxylic acids, (E)-3-(2-aminophenyl)-1-phenylprop-2-en-1-ones, Ag-promoted, decarboxylative cyclization, intramolecular 6π-electrocyclization, quinolines derivatives.

Affiliation:

School of Petrochemical Engineering, and Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Changzhou University, Changzhou 213164, School of Petrochemical Engineering, and Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Changzhou University, Changzhou 213164, School of Petrochemical Engineering, and Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, Changzhou University, Changzhou 213164



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