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Multi-component Preparation of Pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidines Using Solvent-free and HSBM Techniques

Author(s):

Seyyed Jalal Roudbaraki, Morteza Ziyaadini and Majid Ghashang*   Pages 1 - 5 ( 5 )

Abstract:


A simple and clean access to pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidine derivatives using solvent-free and HSBM techniques through the multi-component reaction of 3-methyl-1-phenyl-1H-pyrazol-5-amine, 1-aryl-2-thiocyanatoethan-1-one and aromatic aldehydes is reported. Using 2-hydroxyethan-1-aminium acetate as an ionic liquid get the product in high yields.

Keywords:

Pyrazolo[3, 4-d]thiazolo[3, 2-a]pyrimidine, Thiazolo[3, 2-a]pyrimidine; HSBM technique, 2-hydroxyethan-1-aminium acetate, Ionic liquid

Affiliation:

Department of Chemistry, Lahijan Branch, Islamic Azad University, Lahijan, Department of Marine Chemistry, Faculty of Marine Science, Chabahar Maritime University, Chabahar, Department of Chemistry, Najafabad Branch, Islamic Azad University, P.O. Box: 517; Najafabad



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