Jitander K. Kapoor, Loveena Arora* and Om Prakash Pages 700 - 704 ( 5 )
Various arylethanones including electron-rich aromatic ketones such as o-hydroxyacetophenone and its p-isomer underwent selective side-chain α,α-dibromination using a heterogeneous system consisting of four molar equivalents of copper(II) bromide in chloroform-ethyl acetate under reflux. This study provides the cleanest method for the selective synthesis of several synthetically useful α,α-dibromoketones which are otherwise difficult to prepare.
o/p-Hydroxyacetophenone, heterogeneous system, side-chain dibromination, arylethanones, copper(II) bromide, bromoketone.
Department of Chemistry, National Institute of Technology, Kurukshetra, Haryana, Department of Chemistry, National Institute of Technology, Kurukshetra, Haryana, Department of Chemistry, Kurukshetra University, Kurukshetra, Haryana