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Phosphomolybdic Acid (PMA)-catalyzed One-pot Synthesis of 2,3- Dihydroquinazolines

Author(s):

Chuanhuan Chen, Xuejiao A, Xia Li, Guoli Huang* and Bo Liu*   Pages 1 - 5 ( 5 )

Abstract:


We have developed a new method for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones in good to excellent yields via phosphomolybdic acid (PMA)-catalyzed cyclocondensation of 2- aminobenzamides with aldehydes or ketones in N,N-dimethylformamide (DMF) at room temperature. The present method proves to be efficient in terms of short reaction time, high yield, simple workup and easy purification.

Keywords:

dihydroquinazolinones, phosphomolybdic acid, 2-aminobenzamide, synthesis

Affiliation:

School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming, School of Chemistry and Chemical Engineering, Yunnan Normal University, Kunming



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