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Synthesis of (R)-2-benzylmorpholine employing catalytic stereospecific rearrangement of L-Phenylalaninol

Author(s):

Mandapati Bhargava Reddy and Ramasamy Anandhan*   Pages 1 - 4 ( 4 )

Abstract:


An efficient synthesis of (R)–2-benzylmorpholine has been accomplished starting from L-phenylalaninol by employing stereospecific rearrangement of β-amino alcohol using catalytic amount of (CF3CO)2O as a key step.

Keywords:

Morpholine, Appetite suppressant agent, Stereospecific rearrangement, Debenzylation.

Affiliation:

Department of Organic Chemistry, University of Madras, Guindy campus, Chennai-600 025, Tamil Nadu, Department of Organic Chemistry, University of Madras, Guindy campus, Chennai-600 025, Tamil Nadu



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