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Cu(OAc)2-Promoted Thiolation and Selenylation of C(sp2)-H Bonds Using a 2-Amino Oxazole Directing Group

[ Vol. 16 , Issue. 2 ]

Author(s):

R. Uday Kumar, Kommula Dileep, K. Harsha Vardhan Reddy* and Y.V.D. Nageswar*   Pages 110 - 116 ( 7 )

Abstract:


Cu-catalyzed thiolation or selenylation of aryl C-H bonds with diaryl disulfides and diphenyl diselenides was accomplished using a readily removable directing group. This protocol represents a convenient route for the formation of valuable diaryl sulfides or diphenyl selenides. This simple method gives a variety of functionalized diphenyl sulfides or diphenyl selenides in moderate to good yields in a simple and efficient way.

Keywords:

Diphenyl disulfide/diselenide, directing group, C-H activation, thiolation, selenylation, redox properties.

Affiliation:

Discovery Lab, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Discovery Lab, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Discovery Lab, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, Discovery Lab, Medicinal Chemistry and Pharmacology Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007

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