Ravi Lakkakula, K. Mukkanti and Arnab Roy* Pages 1065 - 1069 ( 5 )
A prudent and scalable synthesis of (±)-Preclamol is described utilizing Michael addition and in-situ reduction/cyclization of an aryl-α-carbethoxy acetonitrile derivative as a key step.
Michael addition, in-situ reduction/cyclization, preclamol, risperidone, alogliptin, ritalin.
GVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad - 500076, Jawaharlal Nehru Technological University, Kukatpally, Hyderabad-500085, GVK Biosciences Private Limited, Plot No. 28 A, IDA Nacharam, Hyderabad - 500076