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K2PdCl4/PPh3-catalyzed Carbon-sulfur Coupling Reaction; An Efficient and One-pot Method to Direct Synthesis of Organic Disulfides/Sulfides from Aryl Halides and Thiourea

[ Vol. 15 , Issue. 11 ]

Author(s):

Masoumeh Raeisi, Fariba Mohammadi, Mohammad Soleiman-Beigi* and Ali Naghipour   Pages 899 - 904 ( 6 )

Abstract:


This work describes an efficient and new catalyst for the one-pot synthesis of organic disulfides/ sulfides via a palladium catalyst in the presence of PPh3 ligands for domino cross-coupling reaction of aryl halides and thiourea and then sulfur-transformation. Finally, the generated aryl thiolate converts to disulfide at normal oxidative and atmospheric conditions in DMF/water. However, thiols convert to unsymmetrical sulfides by one-pot reaction with alkyl halides in PEG/H2O.

Keywords:

Palladium catalyst, organic disulfides/sulfides, cross-coupling reaction, thiourea, K2PdCl4, halides.

Affiliation:

Department of Chemistry, Basic of Sciences Faculty, Ilam University, Ilam, Department of Chemistry, Basic of Sciences Faculty, Ilam University, Ilam, Department of Chemistry, Basic of Sciences Faculty, Ilam University, Ilam, Department of Chemistry, Basic of Sciences Faculty, Ilam University, Ilam

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