Roya Azadi* and Zahra Motamedpoor Pages 801 - 804 ( 4 )
A very simple and efficient procedure for the preparation of primary amides is described from carboxylic acids using Mukaiyama reagent/KNCO in aqueous acetonitrile. Availability of the reagents, simplicity, and easy workup of the reaction crude make this method attractive for organic chemists.
2-Chloro-1-methylpyridinium iodide, acyl isocyanate, amide, carboxylic acid, mukaiyama reagent.
Chemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz, Chemistry Department, Faculty of Science, Shahid Chamran University of Ahvaz, Ahvaz