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Synthesis of Polyfunctionalized Furans by Three-component Reaction Between Arylglyoxals, 1,3-Diketones and Isocyanides

[ Vol. 15 , Issue. 9 ]

Author(s):

Motahareh Heidari, Mohammad Anary-Abbasinejad*, Dadkhoda Ghazanfari and Mohammad Reza Akhgar   Pages 773 - 777 ( 5 )

Abstract:


Three-component reaction between arylglyoxal monohydrates, isocyanides and 1,3- diketones in water is reported. This reaction provides a simple and efficient route for the synthesis of poly-functionalized furan derivatives. The reaction conditions and work-up procedure are simple and products were obtained in good yields.

Keywords:

Arylglyoxal, three-component reaction, furan, isocyanide, 1, 3-diketones, aqueous media.

Affiliation:

Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Department of Chemistry, Vali-e- Asr University, Rafsanjan, 77176, Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman

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