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L-Proline Catalyzed Synthesis of Various N-substituted Urea and Unsymmetrical N,N’-disubstituted Urea

[ Vol. 15 , Issue. 11 ]

Author(s):

Ajit G. Nagarkar and Vikas N. Telvekar*   Pages 926 - 930 ( 5 )

Abstract:


Here, we report a simple and efficient method for the synthesis of different unsymmetrical N,N’-disubstituted urea and N-substituted urea derivatives using L-Proline as a green catalyst. The methodology is applicable for synthesizing various derivatives of phenylurea, diphenyl urea with excellent yield at mild condition.

Keywords:

N-substituted urea, urea, amines, N, N`-disubstituted urea, L-Proline, green catalyst.

Affiliation:

Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400 019, Pharmaceutical Sciences and Technology, Institute of Chemical Technology, Mumbai 400 019

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