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Synthesis of Hitherto Unknown 4,4-Bis(methylthio)but-3-en-2-one-1,1,1,3- d4 and Its Application as 1,3-Dielectrophilic Building Block for the Synthesis of Deuterated Heterocycles and Aromatics

[ Vol. 15 , Issue. 5 ]

Author(s):

T.P. Charanraj, P. Ramachandra, N. Ramesh and H. Junjappa*   Pages 412 - 417 ( 6 )

Abstract:


Acetone-d6 has been transformed for the first time to 4,4-bis(methylthio)but-3-en-2-one- 1,1,1,3-d4. This tetradeutero-α-oxoketenedithioacetal is shown to be an excellent 1,3-dielectrophilic building block for the synthesis of 5- and 6-membered deuterated heterocycles and aromatics.

Keywords:

Acetone-d6, α-oxoketenedithioacetal, 1, 3-dielectrophilic building block, deuterated heterocycles, aromatics, aromatic compounds.

Affiliation:

Chemistry Research Unit, REVA Institute of Science and Management, Bangalore-560064, Department of Chemistry, REVA Institute of Technology and Management, Bangalore-560064, Director Planning, REVA University, Bangalore-560064, Chemistry Research Unit, REVA Institute of Science and Management, Bangalore-560064

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