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Amino Acid Catalyzed Synthesis of 2,3-Dihydroquinazolin-4(1H)-One Derivatives

[ Vol. 15 , Issue. 4 ]

Author(s):

K. Mohammed Mustaque, A. Subramani, T.K. Shabeer, H. Thajudeen and V.S. Jamal Ahamed*   Pages 246 - 250 ( 5 )

Abstract:


A simple, convenient and facile approach for the synthesis of a series of 2,3- dihydroquinazolin-4(1H)-ones in an environmentally benign method has been developed. This method involves a direct cyclocondensation of 2-aminobenzamide with aromatic aldehydes and ketones using aspartic acid as a catalyst in water.

Keywords:

Amino acid, catalyst, 2, 3-Dihydroquinazolin-4(1H)-ones, 2-aminobenzamide, ketones, water.

Affiliation:

PG and Research Dept. of Chemistry, The New College, Chennai-600014, Tamilnadu, PG and Research Dept. of Chemistry, The New College, Chennai-600014, Tamilnadu, PG and Research Dept. of Chemistry, The New College, Chennai-600014, Tamilnadu, PG and Research Dept. of Chemistry, The New College, Chennai-600014, Tamilnadu, PG and Research Dept. of Chemistry, The New College, Chennai-600014, Tamilnadu

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