Elango Kandasamy*, Sankaranarayanan Nagarajan and Tanveer M. Shaikh* Pages 133 - 138 ( 6 )
The Knoevenagel reaction is one of the most useful methods for the synthesis of α,β- unsaturated nitriles. We disclose an efficient protocol for the Knoevenagel reaction of aldehydes with malononitrile catalyzed by 1-alkyl-1,2,4-triazolium salts to afford the corresponding products in excellent yields. The important feature of this reaction is the catalyst; 1-alkyl-1,2,4-triazolium salts are recycled and reused. Furthermore, the reaction conditions are environment friendly and do not produce any hazardous waste.
Aldehyde, benzylidenemalononitrile, Brønsted acid, ionic liquids, Knoevenagel reaction, reusable catalyst, triazolium salts.
Department of Sciences, Amrita School of Engineering Coimbatore, Amrita Vishwa Vidyapeetham, Amrita University, Coimbatore, Deapetment of S&H, PSN Engineering College, Melathediyoor, Tirunelveli, Department of Chemistry, CNCS, Mekelle University, Mekele