Gurusamy Harichandran*, Parkunan Parameswari and Ponnusamy Shanmugam Pages 600 - 605 ( 6 )
An efficient Amberlite IRA-400 Cl resin catalyzed, solvent-free, one-pot synthesis of 1- aryl-1,2-dihydro-3H-naphtho[1,2-e][1,3]oxazin-3-ones via three-component reaction of arylaldehydes, urea, and β-naphthol are described. This method offers advantages such as easy work-up, low environmental impact, shortened reaction times, and high yields. The catalyst recovered was reused four times without significant loss of catalytic activity.
Amberlite IRA-400 Cl resin, naphthoxazin-3-ones, solvent-free conditions, three-component reaction, green catalyst, therapeutic agents.
Department of Polymer Science, University of Madras, Guindy Campus, Chennai 600 025, Department of Polymer Science, University of Madras, Guindy Campus, Chennai 600 025, Organic Chemistry Division, CSIR-Central Leather Research Institute (CLRI), Adyar, Chennai 600 020