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Synthesis of 2,4,5-Triaryl-1H-Imidazoles under Kornblum Oxidative Condition

[ Vol. 15 , Issue. 6 ]

Author(s):

Mohammad Hosein Sayahi, Mina Bahmei, Setareh Moghimi, Mohammad Mahdavi, Loghman Firoozpour and Alireza Foroumadi*   Pages 530 - 533 ( 4 )

Abstract:


2,4,5-Triaryl-1H-imidazoles were synthesized from benzyl bromides under Kornblum oxidative condition. The reaction proceeded via an in situ oxidation followed by condensation to afford the desired products in good yields.

Keywords:

Imidazoles, Kornblum oxidation, benzyl halide, one-pot, three-component reaction, MCRs.

Affiliation:

Department of Chemistry, Payame Noor University (PNU), P.O. Box 19395-3697, Tehran, Department of Chemistry, Payame Noor University (PNU), P.O. Box 19395-3697, Tehran, Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran, Drug Design and Development Research Center, Tehran University of Medical Sciences, Tehran

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