Samereh Seyfi, Faramarz Rostami-Charati, Zinatossadat Hossaini and Mohammad R. Zardoost Pages 409 - 412 ( 4 )
A water-accelerated multicomponent synthesis of organic target molecules has been used as a key method for the preparation of cyclopentadiene derivatives. The three-component condensation reactions of primary amines with alkyl propiolates in the presence of triphenylphosphine in water at 80 °C are developed as efficient and clean green synthetic procedures for the high-yielding preparation of 4-oxo-2,5-cyclopentadiene-1,2-dicarboxylate derivatives.
Cyclopentadiene, primary amines, triphenylphosphine, alkyl propiolates, multi-component reaction.
Department of Chemistry, Faculty of Science, Gonbad Kavous University, P.O. Box 163, Gonbad, Iran.