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A Simple and Highly Efficient Procedure for One-Pot Synthesis of 2- Azetidinones Using 3,5-Dinitrobenzoyl Chloride

[ Vol. 10 , Issue. 9 ]

Author(s):

Alireza Darvishi, Maaroof Zarei and Mohammad Reza Akhgara   Pages 645 - 650 ( 6 )

Abstract:


One-pot synthesis of 2-azetidinones has efficiently been carried out in excellent yields by treatment of imines and substituted acetic acids with 3,5-dinitrobenzoyl chloride in the presence of triethylamine. The method is remarkably convenient and pure products were obtained by simple crystallization.

Keywords:

β -Lactam, 2-Azetidinone, Staudinger reaction, 3, 5-Dinitrobenzoyl chloride, Ketene, Imine.

Affiliation:

Department of Chemistry, Faculty of Science, Kerman Branch, Islamic Azad University, Kerman, Iran; and Department of Chemistry, College of Sciences, Hormozgan University, Bandar Abbas 71961, Iran.



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