Submit Manuscript  

Article Details

Copper and Iron-assisted Palladium-catalyzed Direct Arylation of Azoles with Arylboronic Acids under Ligand and Base-free Conditions

[ Vol. 10 , Issue. 9 ]


Xiang-Mei Wu and Qiu-Xian Shen   Pages 668 - 673 ( 6 )


The direct arylation of azoles with arylboronic acids is effectively promoted by PdCl2 in the presence of copper and iron salts under ligand and base-free conditions. This reaction can be applied to heterocycles such as benzothiazole, benzoxazole, 1-methylbenzimidazole and 4,5-dimethylthiazole with moderate to good yields.


Palladium, copper, iron, arylation, arylboronic acid.


Department of Chemistry, College of Science, Lishui University, Lishui, Zhejiang 323000, China.

Read Full-Text article