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A Very Simple, Highly Efficient and Catalyst-free Procedure for the NFormylation of Amines Using Triethyl orthoformate in Water Under Ultrasound-irradiation

[ Vol. 10 , Issue. 3 ]


Davood Habibi, Hesam Sahebekhtiari, Mahmoud Nasrollahzadeh and Ahmad Taghipour   Pages 209 - 212 ( 4 )


N-Formylation of amines has efficiently been carried out in excellent yields by treatment of amines with triethyl orthoformate in water under ultrasound irradiation. The process is remarkably simple and environmentally benign.


Amines, Aqueous medium, Catalyst-free, N-formylation, Triethyl orthoformate, Ultrasound irradiation


Department of Organic Chemistry, Faculty of Chemistry, Bu Ali University of Iran.

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