Abolfazl Olyaei, Mojgan Zarnegar, Mahdieh Sadeghpour and Mortaza Rezaei Pages 451 - 456 ( 6 )
An efficient solvent and catalyst-free synthesis of new Betti base derivatives via Mannich-type one-pot threecomponent condensation reaction of aminodiazines, salicylaldehyde and naphthols under solvent-free conditions is described. The reactions occur at 80 oC giving high to excellent yields of the products. The work-up procedure is very simple and the products do not require further purification with column chromatography.
Aminodiazine, Betti base, naphthol, salicylaldehyde, solvent-free, three- component, 2-aminopyrimidine, temperature, aminonaphthols
Department of Chemistry, Payame Noor University, PO BOX 19395-3697, Tehran, Iran.